Article
Detailed profiles of histone modification in male germ line cells of the young and aged mice
2019-05-13
Abstract excerpt
Human epidemiological studies have shown paternal aging as one of the risks for neurodevelopmental disorders such as autism in offspring. A recent study has suggested that factors other than de novo mutations due to aging can influence biology of offspring. Here we are focusing on epigenetic alterations in sperm that can influence offspring developmental programs. In this study, we qualitatively and semi-quantitat...
Topics
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- Epigenetics and DNA Methylation
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Genetic Syndromes and Imprinting
- Prenatal Screening and Diagnostics
- Reproductive Biology and Fertility
- Reproductive Health and Technologies
- Sperm and Testicular Function
- Testicular diseases and treatments
Identifiers and source
- Literature Corpus work
- 5cda102e-5e73-501e-943d-e74ac5a0efc9
- DOI
- 10.1101/635961