Article

N-Palmitoyl glycine activates transient receptor potential channel 5 and increases the risk of Brugada syndrome

2024-10-22

Abstract excerpt

<h4>Background</h4> Brugada syndrome (BrS) is an arrhythmic disorder associated with an increased risk of sudden cardiac death; however, current treatment options are limited due to their side effects and variable efficacy. <h4>Methods</h4> In this study, we first employed Mendelian randomization analysis utilizing proteomic, transcriptomic, and metabolomic data to identify potential therapeutic targets for BrS. E...

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Literature Corpus work: 5cbffaa4-4048-5559-a6c1-c3c06ad0da8e
DOI: 10.1101/2024.10.21.24315897

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