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Article

Genetic Exploration of Targeting the Transient Receptor Potential Cation Channel Subfamily Member 6.

Journal of cardiovascular pharmacology - 1 Sept 2025

Graesser Christian, Panyam Nikita, Qian Xiaofeng, Dang Tan An, Niedermeier Benedikt, Winkler Michael, Riechel Johannes, Sharifi M Amin, Noecker Christin, Abrahamian Carla, Dietrich Alexander, Sager Hendrik B, Schunkert Heribert, Li Ling, Kessler Thorsten

Abstract excerpt

ABSTRACT: The transient receptor potential cation channel subfamily member 6 (TRPC6) represents an emerging druggable target with a broad therapeutic spectrum. TRPC6 Inhibitors are currently investigated for focal segmental glomerulosclerosis, acute respiratory distress syndrome due to COVID-19, and pulmonary hypertension. In the cardiovascular system, there is evidence that TRPC6 is critically involved in the...

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Share to TRPC6 gene
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 40497816
DOI: 10.1097/FJC.0000000000001727

Genes

TRPC6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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