Article

Cloned Mice from Fetal Fibroblast Cells Arrested at Metaphase by a Serial Nuclear Transfer1

2001-01-01

Abstract excerpt

Cloning using G0-arrested somatic cells has led to the suggestion that this stage of the cell cycle is necessary for the success of cloning. In this study we report that cloned mice can be generated from fetal fibroblasts arrested at metaphase of the cell cycle. The procedure involves fusing a metaphase-arrested fetal fibroblast to an enucleated oocyte. After parthenogenetic activation a polar body and single dipl...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5cb65892-2d7f-5f08-9025-fe69d2934e17
DOI: 10.1095/biolreprod64.1.44

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Cloned Mice from Fetal Fibroblast Cells Arrested at Metaphase by a Serial Nuclear Transfer1DOI 10.1095/biolreprod64.1.44Read

Production of cloned mice from embryonic stem cells arrested at metaphaseSemantic proximity Read

Mice cloned from embryonic stem cells.Semantic proximity Read

Asymmetric Reprogramming Capacity of Parental Pronuclei in Mouse ZygotesSemantic proximity Read

Production of Cloned Mice and ES Cells from Adult Somatic Cells by Nuclear Transfer: How to Improve Cloning Efficiency?Semantic proximity Read

Functional full-term placentas formed from parthenogenetic embryos using serial nuclear transferSemantic proximity Read

Nuclear transplantation: lessons from frogs and mice.Semantic proximity Read

Phenotypic effects of somatic cell cloning in the mouse.Semantic proximity Read

Chromosome stability differs in cloned mouse embryos and derivative ES cells.Semantic proximity Read

Mouse cloned from embryonic stem (ES) cells synchronized in metaphase with nocodazole.Semantic proximity Read

Nuclear reprogramming of cloned embryos and its implications for therapeutic cloningSemantic proximity Read

Development of Human Cloned Blastocysts Following Somatic Cell Nuclear Transfer with Adult FibroblastsSemantic proximity Read

Early and delayed aspects of nuclear reprogramming during cloningSemantic proximity Read