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Article

Production of cloned mice from embryonic stem cells arrested at metaphase

1 Nov 2001

Abstract excerpt

In mammals, cloned individuals can be produced from somatic cells. The combined use of gene targeting in embryonic stem cells and cloning contributes to the investigation of gene function in mammals. However, one of the major limitations to cloning is the low viability of cloned embryos, leading typically to high rates of pre- and postnatal death. The present study investigated whether cloning efficiency is...

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PMID: 11690533
DOI: 10.1530/rep.0.1220731

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Source receipt: pubmed, retrieved 7 Sept 2026.

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