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Article

Cep57 and Cep57L1 maintain centriole engagement in interphase to ensure centriole duplication cycle.

The Journal of cell biology - 1 Mar 2021

Ito Kei K, Watanabe Koki, Ishida Haruki, Matsuhashi Kyohei, Chinen Takumi, Hata Shoji, Kitagawa Daiju

Abstract excerpt

Centrioles duplicate in interphase only once per cell cycle. Newly formed centrioles remain associated with their mother centrioles. The two centrioles disengage at the end of mitosis, which licenses centriole duplication in the next cell cycle. Therefore, timely centriole disengagement is critical for the proper centriole duplication cycle. However, the mechanisms underlying centriole engagement during...

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Identifiers

PMID: 33492359
DOI: 10.1083/jcb.202005153
PMCID: PMC7836272

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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