Article

Marginal Zone B Cells are Necessary for the Formation of Anti-Donor IgG After Allogeneic Sensitization

2022-09-26

Abstract excerpt

<h4>ABSTRACT</h4> The formation of anti-MHC antibody is a significant barrier to improved outcomes in organ transplantation. Patients with pre-formed anti-HLA antibodies have limited options for suitable donors, and the formation of donor-specific anti-HLA antibodies after transplantation is a harbinger of graft rejection. Despite the recognized importance of anti-HLA antibodies, the mechanisms responsible for th...

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Literature Corpus work: 5c6b6c76-3c2e-5482-8811-911ca4e5a42a
DOI: 10.1101/2022.09.23.509210

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