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Impact of Induction Therapy on Circulating T Follicular Helper Cells and Subsequent Donor-Specific Antibody Formation After Kidney Transplant

7 Dec 2018

Abstract excerpt

Introduction The cellular events that contribute to generation of donor-specific anti-HLA antibodies (DSA) post-kidney transplantation (KTx) are not well understood. Characterization of such mechanisms could allow tailoring of immunosuppression to benefit sensitized patients. Methods We prospectively monitored circulating T follicular helper (cT FH ) cells in KTx recipients who received T-cell depleting...

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PMID: 30899873
DOI: 10.1016/j.ekir.2018.11.020

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