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Distinct roles for LTalpha3 and LTalpha1beta2 produced by B cells contribute to their multi-faceted impact on ileitis

2024-02-26

Abstract excerpt

<title>Abstract</title> <p>B lymphocytes may facilitate chronic inflammation through antibody production or secretion of cytokines, including lymphotoxin (LT)-a<sub>1</sub>b<sub>2</sub> associated with development of lymphoid tissue. Tertiary lymphoid structures (TLS) characterize human and murine ileitis by suppressing outflow from the ileum. Here, we show that B cell-derived secretory IgA protected against ilea...

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Literature Corpus work
5c41710d-dbc0-5a49-bb3f-c27e7f06ea39
DOI
10.21203/rs.3.rs-3962916/v1
Open publication

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Distinct roles for LTalpha3 and LTalpha1beta2 produced by B cells contribute to their multi-faceted impact on ileitisDOI 10.21203/rs.3.rs-3962916/v1
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