Article
Gut Lymphocyte Phenotype Changes After Parenteral Nutrition and Neuropeptide Administration.
Annals of surgery - 1 Jul 2015
Jonker Mark A, Heneghan Aaron F, Fechner John H, Pierre Joseph F, Sano Yoshifumi, Lan Jinggang, Kudsk Kenneth A
Abstract excerpt
OBJECTIVE: To define gut-associated lymphoid tissue (GALT) phenotype changes with parenteral nutrition (PN) and PN with bombesin (BBS). BACKGROUND: PN reduces respiratory tract (RT) and GALT Peyer patch and lamina propria lymphocytes, lowers gut and RT immunoglobulin A (IgA) levels, and destroys established RT antiviral and antibacterial immunity. BBS, an enteric nervous system neuropeptide, reverses PN-induced...
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