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Immune Cytolytic Activity and Strategies for Therapeutic Treatment

2024-01-31

Abstract excerpt

Intratumoral immune cytolytic activity (CYT), measured as the geometric mean of the expression of Granzyme-A (GZMA) and Perforin-1 (PRF1), has emerged as a critical factor in cancer immunotherapy, with significant implications for patient prognosis and treatment outcomes. Here, we review how different immune checkpoint pathways, the composition of Tumor Microenvironment (TME), antigen presentation and metabolic pa...

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Literature Corpus work
5c31ef54-8d0e-544c-aa7d-68e07c2dd100
DOI
10.20944/preprints202401.2227.v1
Open publication

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Immune Cytolytic Activity and Strategies for Therapeutic TreatmentDOI 10.20944/preprints202401.2227.v1
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