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Article

Granzymes expression patterns predict immunotherapy response and identify the heterogeneity of CD8+ T cell subsets

4 Aug 2023

Abstract excerpt

BACKGROUND: Recent studies illustrated the effects of granzymes (GZMs) gene alterations on immunotherapy response of cancer patients. Thus, we aimed to systematically analyze the expression and prognostic value of GZMs for immunotherapy in different cancers, and identified heterogeneity of the GZMs expression-based CD8+ T cell subsets. METHODS: First, we analyzed GZMs expression and prognostic value at pan-cancer...

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PMID: 37545222
DOI: 10.3233/cbm-230036

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