Article

Pleura Organoid Transplantation Facilitates Visceral Pleural Repair through CD133+ Progenitor Cell-Mediated Regeneration

2025-10-31

Abstract excerpt

<title>Abstract</title> <p>Persistent pulmonary air leakage following thoracic surgery remains a significant clinical challenge due to inadequate repair strategies. Here, we establish murine and human pleura organoids as a novel regenerative therapy. Morphological and functional analyses confirm that these organoids retain mesothelial markers and secretory activity critical for pleural homeostasis. Xenotransplant...

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Literature Corpus work: 5c2dadc9-ad9c-5506-8af5-76d2abe8d790
DOI: 10.21203/rs.3.rs-7519690/v1

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