Article

Single-cell transcriptomic analysis of human pleura reveals stromal heterogeneity and informs in vitro models of mesothelioma

2022-12-05

Abstract excerpt

<h4>ABSTRACT</h4> The pleural lining of the thorax regulates local immunity, inflammation and repair. A variety of conditions, both benign and malignant including pleural mesothelioma, can affect this tissue. A lack of knowledge concerning the mesothelial and stromal cells comprising the pleura has hampered the development of targeted therapies. Here we present the first comprehensive single cell transcriptomic a...

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Literature Corpus work: fd94be66-4c0f-5028-9bce-1b6464615558
DOI: 10.1101/2022.12.03.518966

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