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Article

hPSC-derived lung organoids: Potential opportunities and challenges

1 Feb 2023

Abstract excerpt

Three-dimensional hPSC-derived lung organoids resemble the fetal lung stage, making them an excellent model for studying human lung development. However, current hPSC-derived lung organoids remain incomplete as they lack native lung components such as vasculature, neurons and immune cells. This highlights the need to generate more complex hPSC-derived lung organoids that can faithfully mimic native human lungs...

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PMID: 36814627
DOI: 10.1016/j.heliyon.2023.e13498

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