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Genomic Copy Number Variation Profiling of Pleural Effusion cfDNA via LP-WGS for Precision Diagnosis and Prognostic Stratification in Lung Adenocarcinoma-associated Malignant Pleural Effusion running title: cfDNA CNV for LUAD-MPE Diagnosis and Prognosis

2026-07-07

Abstract excerpt

<title>Abstract</title> <p> Background Lung adenocarcinoma (LUAD)-associated malignant pleural effusion (MPE) is an advanced disease hallmark with a median survival of 3–12 months. Current diagnostic strategies suffer from critical limitations: cytological examination has inadequate sensitivity, invasive biopsy is poorly tolerated by some patients, and traditional biomarkers such as carcinoembryonic antigen (CE...

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Literature Corpus work: f128f80a-6c05-5dfb-8acd-20fc977067d0
DOI: 10.21203/rs.3.rs-10131380/v1

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Genomic Copy Number Variation Profiling of Pleural Effusion cfDNA via LP-WGS for Precision Diagnosis and Prognostic Stratification in Lung Adenocarcinoma-associated Malignant Pleural Effusion running title: cfDNA CNV for LUAD-MPE Diagnosis and PrognosisDOI 10.21203/rs.3.rs-10131380/v1Read

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