Article

Regulatory plasticity of the human genome

2024-11-14

Abstract excerpt

Evolutionary turnover in non-coding regions has driven phenotypic divergence during past speciation events and continues to facilitate environmental adaptation through variants. We used a deep learning model to identify the substrates of regulatory turnover using genome wide mutations mimicking three evolutionary pathways: recent history (human-chimp substitutions), modern population (human population variation),...

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Literature Corpus work: 5ba1954d-1226-58e7-8066-79d44befae21
DOI: 10.1101/2024.11.13.623439

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