Article

Fine-mapping candidate neuropsychiatric regulatory variants using cell type-aware comparative genomics

2026-06-19

Abstract excerpt

<h4> Abstract </h4> Measures of nucleotide sequence conservation across species are useful for identifying functional genomic loci, but can fail when regulatory function is maintained, often in a cell type-specific manner, even when sequence is not. We introduce CTACIT, the Cell Type-Aware Conservation Inference Toolkit, to identify trait-associated regulatory variants. CTACIT integrates sequence conservation sc...

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Literature Corpus work: 980c2314-aaae-5bba-93a2-4e3986bcb1da
DOI: 10.64898/2026.06.17.732994

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