Article

Single Cell Analysis of Treatment–Resistant Prostate Cancer: Implications of Cell State Changes for Cell Surface Antigen Targeted Therapies

2024-04-12

Abstract excerpt

<h4>ABSTRACT</h4> Targeting cell surface molecules using radioligand and antibody–based therapies has yielded considerable success across cancers. However, it remains unclear how the expression of putative lineage markers, particularly cell surface molecules, varies in the process of lineage plasticity, wherein tumor cells alter their identity and acquire new oncogenic properties. A notable example of lineage pla...

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Literature Corpus work: 5b87a92f-444b-5528-a89f-4d8174f782a9
DOI: 10.1101/2024.04.09.588340

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