Article

Increased migration and motility in XIAP-null cells mediated by the C-RAF protein kinase

2021-09-29

Abstract excerpt

The product encoded by the X-linked inhibitor of apoptosis (XIAP) gene is a multi-functional protein which not only controls caspase-dependent cell death, but also participates in inflammatory signalling, copper homeostasis, response to hypoxia and control of cell migration. Deregulation of XIAP, either by elevated expression or inherited genetic deletion, is associated with several human disease states. Reconcili...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5b6dfa40-e9e2-56f9-a93a-69b61ab9ce69
DOI: 10.21203/rs.3.rs-923703/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Increased migration and motility in XIAP-null cells mediated by the C-RAF protein kinaseDOI 10.21203/rs.3.rs-923703/v1Read

Regulation of Cell Death and Immunity by XIAP.Semantic proximity Read

X-Linked Inhibitor of Apoptosis Protein â€“ A Critical Death Resistance Regulator and Therapeutic Target for Personalized Cancer TherapySemantic proximity Read

A novel role for inhibitor of apoptosis (IAP) proteins as regulators of endothelial barrier function by mediating RhoA activation.Semantic proximity Read

Nucleotide-binding oligomerization domain (NOD) signaling defects and cell death susceptibility cannot be uncoupled in X-linked inhibitor of apoptosis (XIAP)-driven inflammatory disease.Semantic proximity Read

Characterization of XIAP-Deficient MiceSemantic proximity Read

FAST is a survival protein that senses mitochondrial stress and modulates TIA-1-regulated changes in protein expression.Semantic proximity Read

The Second Mitochondrial Activator of Caspases (SMAC) regulates growth, inflammation and mitochondrial integrity in cancer cellsSemantic proximity Read

Recent advances in understanding inhibitor of apoptosis proteinsSemantic proximity Read

Phosphorylation of XIAP by CDK1-cyclin-B1 controls mitotic cell death.Semantic proximity Read

Identification of a novel splice variant of X-linked inhibitor of apoptosis-associated factor 1.Semantic proximity Read

Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the familySemantic proximity Read

xIAP induces cell-cycle arrest and activates nuclear factor-kappaB : new survival pathways disabled by caspase-mediated cleavage during apoptosis of human endothelial cells.Semantic proximity Read