Article

Are there causal associations between obsessive-compulsive disorder and cardiometabolic phenotypes? A genetic correlation and bi-directional Mendelian randomization study

2025-04-10

Abstract excerpt

<h4>ABSTRACT</h4> In epidemiological studies, obsessive-compulsive disorder (OCD) is robustly associated with increased risk of cardiometabolic disorders, including cardiovascular diseases, type 2 diabetes, and obesity. However, the mechanisms behind these associations are unclear. We conducted genetic correlation analyses to explore shared genetic etiology and bi-directional summary-level Mendelian randomization...

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Literature Corpus work: 5b6aed40-a1db-5f9a-82dd-ec6822787953
DOI: 10.1101/2025.04.08.25325472

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