Article
Mendelian randomization analyses identify bidirectional causal relationships of obesity with psychiatric disorders.
Journal of affective disorders - 15 Oct 2023
Chen Wenhui, Feng Jia, Jiang Shuwen, Guo Jie, Zhang XiaoLin, Zhang Xiaoguan, Wang Cunchuan, Ma Yi, Dong Zhiyong
Abstract excerpt
BACKGROUND: Obesity have been showed to be strongly associated with psychiatric disorders, but the exact causality and the direction of the relationship remain inconclusive. Thus, we aimed to identify the causal associations between obesity and psychiatric disorders using two-sample Mendelian randomization (MR). METHODS: Single-nucleotide polymorphisms associated with obesity, including body mass index (BMI),...
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