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Exploring the Causal Relationships Between Anxiety, Obesity, and Hypertension: A Two-Sample Mendelian Randomization Study.

American journal of hypertension - 16 Sept 2025

Fan Caini, Wang Jie, Guo Baozhu, Wang Shanshan, Kong Dehui, Liu Min, Jiang Ling, Li Ling, Zhao Haiying

Abstract excerpt

BACKGROUND: Both anxiety and obesity have been implicated in hypertension development, with emerging evidence suggesting metabolic risk factors as potential mediators. Notably, obesity may partially mediate the link between anxiety and hypertension. However, the causal relationships among these factors remain unclear. To address this, we conducted a two-sample Mendelian randomization (MR) analysis to elucidate...

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PMID: 40357578
DOI: 10.1093/ajh/hpaf072

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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