Article

Neural stem cells respond to extracellular succinate via SUCNR1/GPR91 to ameliorate chronic neuroinflammation

2018-01-01

Abstract excerpt

Neural stem cell (NSC) transplantation induces recovery in animal models of central nervous system (CNS) diseases, in part by modulating adaptive and innate immune responses. Since metabolism governs the phenotype and function of immune cells, the aim of this thesis was to investigate whether NSCs have the ability to regulate the immunometabolic components underpinning neuroinflammation. Herein I have identified a...

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Literature Corpus work: 5b688d5a-9587-5d6a-8aed-668b5a8f9102
DOI: 10.17863/cam.24280

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