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Article

Succinate, an intermediate in metabolism, signal transduction, ROS, hypoxia, and tumorigenesis.

Biochimica et biophysica acta - 1 Aug 2016

Tretter Laszlo, Patocs Attila, Chinopoulos Christos

Abstract excerpt

Succinate is an important metabolite at the cross-road of several metabolic pathways, also involved in the formation and elimination of reactive oxygen species. However, it is becoming increasingly apparent that its realm extends to epigenetics, tumorigenesis, signal transduction, endo- and paracrine modulation and inflammation. Here we review the pathways encompassing succinate as a metabolite or a signal and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26971832
DOI: 10.1016/j.bbabio.2016.03.012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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