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Gut flora-derived succinate exacerbates Allergic Airway Inflammation by promoting protein succinylation

30 Mar 2025

Abstract excerpt

Allergic airway inflammation (AAI) is a prevalent respiratory disorder that affects a vast number of individuals globally. There exists a complex interplay among inflammation, immune responses, and metabolic processes, which is of paramount importance in the pathogenesis of AAI. Metabolic dysregulation and protein translational modification (PTM) are well-recognized hallmarks of diseases, playing pivotal roles in...

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PMID: 40174477
DOI: 10.1016/j.redox.2025.103623

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