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Tools for genetic manipulation of the endemic fungal pathogen, <i>Emergomyces africanus,</i> and the application of a fluorescent reporter strain in infection models

2025-11-14

Abstract excerpt

<h4> Abstract </h4> Emergomyces africanus is a thermally dimorphic fungal pathogen endemic to Southern Africa which can cause fatal systemic infections in persons with advanced HIV disease. Its mechanisms of pathogenesis are not well understood. Characterisation of virulence traits in this pathogen requires appropriate molecular tools for genetic manipulation. Molecular technologies developed for the transformat...

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Literature Corpus work
5b51ed45-8262-5e88-bc45-0625572a9e85
DOI
10.1101/2025.11.14.688410
Open publication

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Tools for genetic manipulation of the endemic fungal pathogen, <i>Emergomyces africanus,</i> and the application of a fluorescent reporter strain in infection modelsDOI 10.1101/2025.11.14.688410
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