Article

The receptor VLDLR binds East Equine Encephalitis virus through multiple distinct modes

2023-11-30

Abstract excerpt

Eastern Equine Encephalitis virus (EEEV) is an alphavirus that can cause severe diseases in infected humans. The very low-density lipoprotein receptor (VLDLR) was recently identified as a receptor of EEEV. Herein, we performed cryo-electron microscopy structural and biochemistry studies on the specific interactions between EEEV and VLDLR. Our results show that VLDLR binds EEEV at three different sites A, B and C t...

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Literature Corpus work: 5b0ebfcc-4f0c-5cd1-9c0b-ad151c1ce223
DOI: 10.1101/2023.11.30.569340

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