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LDL receptor in alphavirus entry: structural analysis and implications for antiviral therapy

8 Jun 2024

Abstract excerpt

Various low-density lipoprotein receptors (LPRs) have been identified as entry factors for alphaviruses, and structures of the corresponding virion-receptor complexes have been determined. Here, we analyze the similarities and differences in the receptor binding modes of multiple alphaviruses to understand their ability to infect a wide range of hosts. We further discuss the challenges associated with the...

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PMID: 38851803
DOI: 10.1038/s41467-024-49301-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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