Article

TIMP-1 attenuates the development of cutaneous inflammation-induced evoked and ongoing pain through receptor-mediated cell signaling

2019-02-04

Abstract excerpt

<h4>ABSTRACT</h4> Unresolved inflammation is a significant predictor for developing chronic pain, and targeting the mechanisms underlying inflammation offers opportunities for therapeutic intervention. During inflammation, matrix metalloproteinase (MMP) activity contributes to tissue remodeling and inflammatory signaling through proteolytic maturation of cytokines. MMP activity is regulated by tissue inhibitors o...

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Literature Corpus work: 5afcada9-4d6b-5688-a5f8-b62bc6b66436
DOI: 10.1101/540724

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