MC1R reduces scarring and rescues stalled healing in a preclinical chronic wound model

Abstract excerpt

Cutaneous healing results in scarring with significant functional and psychological sequelae, while chronic non-healing wounds represent repair failure often with devastating consequences, including amputation and death. Due to a lack of effective therapies, novel interventions addressing scarring and chronic wounds are urgently needed. Here, we demonstrate that harnessing melanocortin 1 receptor with a selective...

Topics

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• Biomedical Research
• Blotting, Western
• Chronic Disease
• Forecasting
• Inflammation Mediators
• Mutation
• Wound Healing
• Wounds and Injuries

Identifiers and source

Literature Corpus work

75c41f37-1914-54d2-a004-d04748ad08fa

DOI

10.1101/2022.11.30.518516