Article
TIMP3 is a CLOCK‐dependent diurnal gene that inhibits the expression of UVB‐induced inflammatory cytokines in human keratinocytes
27 Nov 2017
Abstract excerpt
As the outermost physical barrier of an organism, the skin is diurnally exposed to UV radiation (UVR). Recent studies have revealed that the skin exhibits a circadian rhythm in various functions, and this oscillation is disturbed and reset via a strong environmental cue, the UVR. However, a molecular link between circadian perturbation by UVR and UVR-induced cellular responses has not been investigated. We...
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