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Article

Metalloproteinase MT5-MMP is an essential modulator of neuro-immune interactions in thermal pain stimulation.

Proceedings of the National Academy of Sciences of the United States of America - 22 Sept 2009

Folgueras Alicia R, Valdés-Sánchez Teresa, Llano Elena, Menéndez Luis, Baamonde Ana, Denlinger Bristol L, Belmonte Carlos, Juárez Lucía, Lastra Ana, García-Suárez Olivia, Astudillo Aurora, Kirstein Martina, Pendás Alberto M, Fariñas Isabel, López-Otín Carlos

Abstract excerpt

Peripheral interactions between nociceptive fibers and mast cells contribute to inflammatory pain, but little is known about mechanisms mediating neuro-immune communication. Here we show that metalloproteinase MT5-MMP (MMP-24) is an essential mediator of peripheral thermal nociception and inflamm...

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Identifiers

PMID: 19805319
DOI: 10.1073/pnas.0908507106
PMCID: PMC2752566

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19805319-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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