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Single-cell transcriptome analysis of CD34 <sup>+</sup> stem cell-derived myeloid cells identifies a CFU-GEMM-like population permissive to human cytomegalovirus infection

2018-10-08

Abstract excerpt

<h4>ABSTRACT</h4> Myeloid cells are important sites of lytic and latent infection by human cytomegalovirus (CMV). We previously showed that only a small subset of myeloid cells differentiated from CD34 + hematopoietic stem cells is permissive to CMV replication, underscoring the heterogeneous nature of these populations. The exact identity of susceptible and resistant cell types, and the cellular features charac...

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Literature Corpus work
5af44715-954a-5545-a7cb-fa5871d18f9d
DOI
10.1101/438457
Open publication

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Single-cell transcriptome analysis of CD34 <sup>+</sup> stem cell-derived myeloid cells identifies a CFU-GEMM-like population permissive to human cytomegalovirus infectionDOI 10.1101/438457
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