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Article

Genetic epidemiology and Mendelian randomization for informing disease therapeutics: conceptual and methodological challenges

2017-05-08

Abstract excerpt

The past decade has been proclaimed as a hugely successful era of gene discovery through the high yields of many genome-wide association studies (GWAS). However, much of the perceived benefit of such discoveries lies in the promise that the identification of genes that influence disease would directly translate into the identification of potential therapeutic targets (1-4), but this has yet to be realised at a lev...

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Literature Corpus work
5aebbdba-663d-527c-8b46-d2fba75ba96d
DOI
10.1101/126599
Open publication

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Genetic epidemiology and Mendelian randomization for informing disease therapeutics: conceptual and methodological challengesDOI 10.1101/126599
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