Article

Functional characterisation of the human S1P₄G protein-coupled receptor

2003-01-01

Abstract excerpt

The human G protein-coupled receptor (GPCR) S1P4 (formerly named Edg6) was identified as an orphan receptor and assigned to the Edg family on the basis of sequence similarity with other Edg receptors. S1P4 was recently shown to couple to Gαi and Gα12/13 G proteins in response to stimulation by the lysophospholipid, sphingosine-1-phosphate (S1P). This thesis describes functional characterisation of the S1P4 recepto...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5acd86cd-f381-51c0-832d-d4c8b38425a9
DOI: 10.21954/ou.ro.0000f56a

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Functional characterisation of the human S1P₄G protein-coupled receptorDOI 10.21954/ou.ro.0000f56aRead

Advances in the molecular level understanding of G-protein coupled receptor.Semantic proximity Read

G‐protein‐coupled receptors: past, present and futureSemantic proximity Read

<i>In vitro</i> profiling of orphan G protein coupled receptor (GPCR) constitutive activitySemantic proximity Read

Lysophospholipid G protein-coupled receptors.Semantic proximity Read

In vitro profiling of orphan G protein coupled receptor (GPCR) constitutive activitySemantic proximity Read

Modifying ligand-induced and constitutive signaling of the human 5-HT4 receptor.Semantic proximity Read

Transmembrane protein CD69 acts as an S1PR1 agonistSemantic proximity Read

Emerging concepts of guanine nucleotide-binding protein-coupled receptor (GPCR) function and implications for high throughput screening.Semantic proximity Read

Identification of cDNAs encoding two G protein‐coupled receptors for lysosphingolipids1Semantic proximity Read

Isolation of Three Novel Human Genes Encoding G Protein-Coupled ReceptorsSemantic proximity Read

Reprogramming G protein coupled receptor structure and function.Semantic proximity Read

Functional selectivity of G-protein-coupled receptors: From recombinant systems to native human cellsSemantic proximity Read