Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of cDNAs encoding two G protein‐coupled receptors for lysosphingolipids1

17 Nov 1997

Abstract excerpt

The structural similarity of lysosphingolipids to lysophosphatidic acid (LPA) prompted a sequence-based search for lysosphingolipid receptors using cDNA sequence of the Edg2 human LPA receptor. Two closely related G protein-coupled receptors, rat H218 and human Edg3, are highly similar to Edg2. When overexpressed in Jurkat cells, H218 and Edg3 activated serum response element-driven transcriptional reporter gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Erythrocyte Function and Pathophysiology
Share to Lipid Membrane Structure and Behavior
Share to Sphingolipid Metabolism and Signaling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9409733
DOI: 10.1016/s0014-5793(97)01301-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of cDNAs encoding two G protein‐coupled receptors for lysosphingolipids1PMID 9409733Read ↗

Lysophospholipid G protein-coupled receptors.Semantic proximity Read ↗

Cell surface receptors in lysophospholipid signaling.Semantic proximity Read ↗

Functional characterisation of the human S1P₄G protein-coupled receptorSemantic proximity Read ↗

In vivo roles of lysophospholipid receptors revealed by gene targeting studies in mice.Semantic proximity Read ↗

Cyclic phosphatidic acid is produced by GDE7 in the ER lumen as a lysophospholipid mediatorSemantic proximity Read ↗

Lysophosphatidic acid receptors in cancer pathobiology.Semantic proximity Read ↗

Distinct glycerophospholipids potentiate Gsα-activated adenylyl cyclase activitySemantic proximity Read ↗

Functional characterization of lysophosphatidic acid receptor 1 mutants identified in rat cancer tissues.Semantic proximity Read ↗

Characterization of lpa(2) (Edg4) and lpa(1)/lpa(2) (Edg2/Edg4) lysophosphatidic acid receptor knockout mice: signaling deficits without obvious phenotypic abnormality attributable to lpa(2).Semantic proximity Read ↗

Identification of residues responsible for ligand recognition and regioisomeric selectivity of lysophosphatidic acid receptors expressed in mammalian cells.Semantic proximity Read ↗

Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, LP(B3)/EDG-3.Semantic proximity Read ↗

Specific Oxylipins Enhance Vertebrate Hematopoiesis via the Receptor GPR132Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.