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Advantageous Antibody Microarray Fabrication Through DNA-Directed Immobilization: A Step Toward Use of Extracellular Vesicles in Diagnostics

2020-05-04

Abstract excerpt

An optimized general protocol for DNA-protein ligation is provided and the conjugates are used to convert DNA arrays into antibody microarrays. Arrays obtained through DDI were used to capture and characterize extracellular vesicles (EVs), an emerging class of biomarkers. The proposed platform was tested against commercially available antibody microarrays, showing good performance combined with ease of fabric...

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Literature Corpus work
5acb67a2-066f-52ae-acb4-8478fbfe28b7
DOI
10.26434/chemrxiv.12227255.v1
Open publication

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Advantageous Antibody Microarray Fabrication Through DNA-Directed Immobilization: A Step Toward Use of Extracellular Vesicles in DiagnosticsDOI 10.26434/chemrxiv.12227255.v1
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