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Extensive surface protein profiles of extracellular vesicles from cancer cells may provide diagnostic signatures from blood samples

1 Jan 2016

Abstract excerpt

Extracellular vesicles (EV) are membranous particles (30-1,000 nm in diameter) secreted by cells. Important biological functions have been attributed to 2 subsets of EV, the exosomes (bud from endosomal membranes) and the microvesicles (MV; bud from plasma membranes). Since both types of particles contain surface proteins derived from their cell of origin, their detection in blood may enable diagnosis and...

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PMID: 27086589
DOI: 10.3402/jev.v5.25355

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