Article

Single-cell gene expression prediction from DNA sequence at large contexts

2023-07-28

Abstract excerpt

Human genetic variants impacting traits such as disease susceptibility frequently act through modulation of gene expression in a highly cell-type-specific manner. Computational models capable of predicting gene expression directly from DNA sequence can assist in the interpretation of expression-modulating variants, and machine learning models now operate at the large sequence contexts required for capturing long-r...

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Literature Corpus work: 38d32bf7-601b-5443-a989-4257903a1c0b
DOI: 10.1101/2023.07.26.550634

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