Article
The human myeloproliferative disorders : molecular pathogenesis and clonal heterogeneity
2009-01-01
Abstract excerpt
The classical myeloproliferative disorders (MPD), comprising essential thrombocythaemia (ET), polycythaemia vera (PV) and idiopathic myelofibrosis (IMF), are clonal premalignant haematopoietic neoplasms associated with activating mutations in signalling pathway molecules and a variable tendency to develop acute myeloid leukaemia (AML). This thesis examined genotype-phenotype associations of JAK2 and MPL mutations,...
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Identifiers and source
- Literature Corpus work
- 5a9d0c9a-2596-5997-bbd9-9cd5f6f55ff1
- DOI
- 10.17863/cam.16447