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Article

Genotype-phenotype interactions in the myeloproliferative neoplasms.

Hematology/oncology clinics of North America - 1 Oct 2012

Godfrey Anna L, Green Anthony R

Abstract excerpt

The chronic myeloproliferative neoplasms (MPNs) are clonal disorders characterized by overproduction of mature myeloid cells. They share associations with molecular abnormalities such as the JAK2V617F mutation but are distinguished by important phenotypic differences. This review first considers the factors that may influence phenotype in JAK2-mutated MPNs, especially polycythemia vera (PV) and essential...

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Genotype
Janus Kinase 2
Mutation
Myeloproliferative Disorders
Phenotype
Polycythemia Vera

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Thrombocythemia, Essential

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Identifiers

PMID: 23009934
DOI: 10.1016/j.hoc.2012.07.003

Genes

JAK2
MPL

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