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Genetic architecture of gene regulation in Indonesian populations identifies QTLs associated with local ancestry and archaic introgression

2020-09-25

Abstract excerpt

Lack of diversity in human genomics limits our understanding of the genetic underpinnings of complex traits, hinders precision medicine, and contributes to health disparities. To map genetic effects on gene regulation in the underrepresented Indonesian population, we have integrated genotype, gene expression, and CpG methylation data from 115 participants across three island populations that capture the major sour...

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Identifiers and source

Literature Corpus work
5a69e65f-481c-522b-9d8d-734c4ddb6170
DOI
10.1101/2020.09.25.313726
Open publication

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Genetic architecture of gene regulation in Indonesian populations identifies QTLs associated with local ancestry and archaic introgressionDOI 10.1101/2020.09.25.313726
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