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Mapping the gene regulatory landscape of archaic hominin introgression in modern Papuans

2025-05-04

Abstract excerpt

Interbreeding between anatomically modern humans and archaic hominins has contributed to the genomes of present-day human populations. However, our understanding of the specific gene regulatory consequences of Neanderthal, and particularly, Denisovan introgression is limited. Here, we used a massively parallel reporter assay to investigate the regulatory effects of 25,869 high-confidence introgressed SNPs segregat...

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Literature Corpus work
32fc5ba9-5039-5fad-95c8-654accdbbc2f
DOI
10.1101/2025.05.04.652069
Open publication

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Mapping the gene regulatory landscape of archaic hominin introgression in modern PapuansDOI 10.1101/2025.05.04.652069
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