Article

Genome-wide DNA methylation and gene expression patterns reflect genetic ancestry and environmental differences across the Indonesian archipelago

2019-07-16

Abstract excerpt

Indonesia is the world’s fourth most populous country, host to striking levels of human diversity, regional patterns of admixture, and varying degrees of introgression from both Neanderthals and Denisovans. However, it has been largely excluded from the human genomics sequencing boom of the last decade. To serve as a benchmark dataset of molecular phenotypes across the region, we generated genome-wide CpG methylat...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2562c337-94a6-580a-ae53-bbd3832ce74a
DOI: 10.1101/704304

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genome-wide DNA methylation and gene expression patterns reflect genetic ancestry and environmental differences across the Indonesian archipelagoDOI 10.1101/704304Read

Genome-wide DNA methylation and gene expression patterns reflect genetic ancestry and environmental differences across the Indonesian archipelago.Semantic proximity Read

Genetic architecture of gene regulation in Indonesian populations identifies QTLs associated with local ancestry and archaic introgressionSemantic proximity Read

Ancestral and environmental diversity shape the immune landscape in IndonesiaSemantic proximity Read

Profiling genetically driven alternative splicing across the Indonesian archipelago.Semantic proximity Read

Profiling genetically driven alternative splicing across the Indonesian ArchipelagoSemantic proximity Read

The population genomic landscape of human genetic structure, admixture history and local adaptation in Peninsular Malaysia.Semantic proximity Read

Mapping the gene regulatory landscape of archaic hominin introgression in modern Papuans.Semantic proximity Read

Epigenetic Variability across Human Populations: A Focus on DNA Methylation Profiles of the KRTCAP3, MAD1L1 and BRSK2 Genes.Semantic proximity Read

DNA methylation contributes to natural human variation.Semantic proximity Read

Mapping the gene regulatory landscape of archaic hominin introgression in modern PapuansSemantic proximity Read

Denisovan introgression has shaped the immune system of present-day PapuansSemantic proximity Read

Exploring the Genetic Basis of Human Population Differences in DNA Methylation and their Causal Impact on Immune Gene RegulationSemantic proximity Read