Article

Fetal liver CD34+ contain human immune and endothelial progenitors and mediate solid tumor rejection in NOG mice

2024-01-03

Abstract excerpt

<title>Abstract</title> <p>Background Transplantation of CD34<sup>+</sup> hematopoietic stem and progenitor cells (HSPC) into immunodeficient mice is an established method to generate humanized mice harbouring a human immune system. Different sources and methods for CD34<sup>+</sup> isolation have been employed by various research groups, resulting in customized models that are difficult to compare. A more detai...

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Literature Corpus work: 5a515eef-85c1-59d6-952a-15e3c6dcebc5
DOI: 10.21203/rs.3.rs-3757024/v1

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