Article
Identification of cancer-related genes and motifs in the human gene regulatory network.
IET systems biology - 1 Aug 2015
Carson Matthew B, Gu Jianlei, Yu Guangjun, Lu Hui
Abstract excerpt
The authors investigated the regulatory network motifs and corresponding motif positions of cancer-related genes. First, they mapped disease-related genes to a transcription factor regulatory network. Next, they calculated statistically significant motifs and subsequently identified positions within these motifs that were enriched in cancer-related genes. Potential mechanisms of these motifs and positions are...
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