Article

Parkin promotes airway inflammatory response to interferon gamma

2023-04-24

Abstract excerpt

<h4>Background: </h4> Increased type 2 interferon (i.e., IFN-γ) signaling has been shown to be involved in airway inflammation in a subset of asthma patients who often show high levels of airway neutrophilic inflammation and poor response to corticosteroid treatment. How IFN-γ mediates airway inflammation in a mitochondrial dysfunction setting (e.g., Parkin up-regulation) remains poorly understood. The goal of thi...

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Literature Corpus work: 5a11acf4-9e01-5a56-9a3b-a8816394d454
DOI: 10.21203/rs.3.rs-2838551/v1

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