Article

Identifying molecular pathways of type 2 diabetes using proteomics, metabolic, and anthropometric profiles in UK and Chinese adults

2025-12-27

Abstract excerpt

<h4>Introduction: </h4> Proteogenomic analyses in large biobanks provide opportunities to improve understanding of the aetiology of type 2 diabetes (T2D) and to identify potential therapeutic targets. Methods We identified proteins (Olink Explore) associated with glycaemic traits and/or T2D with observational designs in UK Biobank (UKB_EUR, n =33,301). Bayesian non_negative matrix factorisation (bNMF) was applied...

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Literature Corpus work: 59e0f318-7cbc-5579-825e-920f7220e1b0
DOI: 10.64898/2025.12.19.25342701

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