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Proteome-wide Mendelian randomization and colocalization analysis identify therapeutic targets for cutaneous melanoma

2025-03-11

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Cutaneous melanoma (CM) is the deadliest form of skin cancer. Mendelian randomization (MR) and local analysis have been widely used in the search for therapeutic targets for diseases. <bold>Methods:</bold> Plasma proteins data were obtained from the UK Biobank Pharmaceutical Proteomics Project (UKB-PPP) database. The GWAS data for CM were extracted from the Finn...

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Literature Corpus work
59697ab9-7f71-52dd-8a3d-1d88f4c1ac34
DOI
10.21203/rs.3.rs-6171084/v1
Open publication

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Proteome-wide Mendelian randomization and colocalization analysis identify therapeutic targets for cutaneous melanomaDOI 10.21203/rs.3.rs-6171084/v1
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